Genome-editing record smashed with 13,000 edits made in one cell

https://www.newscientist.com/article/2197656-genome-editing-record-smashed-with-13000-edits-made-in-one-cell/

CRISPR gene editing changes the sequence of DNA

CRISPR gene editing changes the sequence of DNA

CARLOS CLARIVAN/SCIENCE PHOTO LIBRARY

A team has used CRISPR to make a record-breaking 13,200 changes to the DNA of a single human cell. The feat takes us a step closer to being able to thoroughly rewrite the genomes of our cells and other organisms.

Half of our genomes – the complete set of DNA inside our cells – consist of hundreds of thousands of copies of genetic parasites called transposons. These transposons code for genes that copy and paste themselves from one location in the genome to …